Now, More Than Ever, Proteomics Needs Better Chromatography.

Police Interpreting: A View from the Australian Context

In the global village of today, more people have been moving and migrating than ever before creating a need for better communication. Thus community interpreting rose as a specialization serving the needs of members of the community who are unable to communicate with the system. Within this broad field of interpreting the specialist area of legal interpreting assumed a high position. However, l...

High Stakes Require More Than Just Talk: What to Do About Corruption in Health Systems; Comment on “We Need to Talk About Corruption in Health Systems”

Reluctance to talk about corruption is an important barrier to action. Yet the stakes of not addressing corruption in the health sector are higher than ever. Corruption includes wrongdoing by individuals, but it is also a problem of weak institutions captured by political interests, and underfunded, unreliable administrative systems and healthcare delivery models. We ur...

Comparison of HPLC-Chip/MS with conventional nanoflow LC/MS for proteomic analyses

Nanoflow LC/MS is commonly used for protein identification and biomarker discovery, but setting up and maintaining the intricate LC plumbing can be a challenge. The Agilent HPLC-Chip represents breakthrough technology that integrates nanoflow HPLC columns, associated connections, and a nanoelectrospray emitter on a single, small, reusable microfluidic chip. The HPLC-Chip and a companion HPLCChi...

The world needs midwives now more than ever.

Hydrophilic interaction chromatography reduces the complexity of the phosphoproteome and improves global phosphopeptide isolation and detection.

The diversity and complexity of proteins and peptides in biological systems requires powerful liquid chromatography-based separations to optimize resolution and detection of components. Proteomics strategies often combine two orthogonal separation modes to meet this challenge. In nearly all cases, the second dimension is a reverse phase separation interfaced directly to a mass spectrometer. Her...